Name: Complement factors (H) into thrombosis
Creator: Michael Holinstat
Keywords: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Humans, Immunologic Factors, Thrombosis, Complement Activation, 7. Clean energy, 3. Good health

descriptionPublicationkeyboard_double_arrow_right Article 02 Mar 2017 English Publisher:American Society of HematologyJournal:Blood, volume 129, pages 1,065-1,066 (issn: 0006-4971, eissn: 1528-0020,

Authors: Michael Holinstat;

doi: 10.1182/blood-2017-01-761528

pmid: 28254823

Complement factors (H) into thrombosis

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Abstract

In this issue of Blood, Ueda et al demonstrate that a mutation in factor H (FH) disrupts host cell interactions, leading to dysregulation of complement, systemic thrombotic angiopathy, and hemolytic uremic syndrome.1

Related Organizations

University of Michigan–Flint
United States
University of Michigan–Ann Arbor
United States

Keywords

Humans, Immunologic Factors, Thrombosis, Complement Activation

1 Research products, page 1 of 1

Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation
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