Hereditary systemic immunoglobulin light-chain amyloidosis
Copyright policy )Hereditary systemic immunoglobulin light-chain amyloidosis
Key PointsProtein and DNA analyses reveal that mutation in the immunoglobulin κ light-chain constant region gene may cause hereditary amyloidosis. Sequencing of immunoglobulin light-chain constant region genes is indicated for patients with AL amyloidosis and no evidence of a plasma cell dyscrasia.
- Indiana University – Purdue University Indianapolis United States
- Richard L. Roudebush VA Medical Center United States
- VA Healthcare System Serving Ohio, Indiana and Michigan United States
- Veterans Health Administration United States
- Indiana University United States
amyloidosis, Male, Base Sequence, Ig constant region gene, DNA Mutational Analysis, Molecular Sequence Data, amyloid, Middle Aged, Pedigree, Immunoglobulin kappa-Chains, Mutation, Humans, Female, Genetic Predisposition to Disease, Amino Acid Sequence, Amyloidosis, Familial, Aged
amyloidosis, Male, Base Sequence, Ig constant region gene, DNA Mutational Analysis, Molecular Sequence Data, amyloid, Middle Aged, Pedigree, Immunoglobulin kappa-Chains, Mutation, Humans, Female, Genetic Predisposition to Disease, Amino Acid Sequence, Amyloidosis, Familial, Aged
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