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Bone Resorption in Human Cholesteatomas

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1982 English Publisher:SAGE PublicationsJournal:Annals of Otology, Rhinology & Laryngology, volume 91, pages 131-135 (issn: 0003-4894, eissn: 1943-572X,

Authors: Erik Dabelsteen; Christian H. Sørensen; Martin Balslev Jorgensen; Paul Bretlau;

doi: 10.1177/000348948209100201

pmid: 7081873

Bone Resorption in Human Cholesteatomas

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Abstract

In vivo studies of different aspects of bone resorption in human cholesteatomas are described in the immunodeficient “nude” mice. Cholesteatoma membranes were transplanted into the middle ear cavities of the mice. After 21–28 days, growth of cholesteatoma tissue could be demonstrated in 8 of 13 animals. In 7 of these 8 animals bone resorption of the labyrinthine wall and ossicles could be demonstrated; resorption with acute inflammation was found in only two animals. The cellular mechanism in relation to bone resorption is discussed.

Keywords

Adult, Adolescent, Ear, Middle, Mice, Nude, Middle Aged, Mice, Child, Preschool, Ear, Inner, Animals, Humans, Bone Resorption, Child, Cholesteatoma, Ear Neoplasms, Neoplasm Transplantation, Aged, Ear Ossicles

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	13
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average