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Intrauterine Blood Transfusion: Current Indications and Associated Risks

Authors: Lindenburg, I.T.M.; Kamp, I.L. van; Oepkes, D.;

Intrauterine Blood Transfusion: Current Indications and Associated Risks

Abstract

Fetal anemia is a serious complication in pregnancy and associated with perinatal mortality and morbidity. During 25 years of worldwide experience with intravascular intrauterine blood transfusion, a variety of indications have been described. Intrauterine transfusion (IUT) treatment is considered most successful for fetal anemia due to red cell alloimmunization. Moreover, the use of this procedure has also been reported in pregnancies with parvovirus B19 infection, fetomaternal hemorrhage and placental chorioangiomas, for example. This review focuses on the current indications of intrauterine blood transfusions. In addition, we describe the potential complications of IUT treatment.

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Keywords

Placenta Diseases, Blood Transfusion, Intrauterine, Chorioangioma, Twin-twin transfusion syndrome, Parvovirus B19, Risk Assessment, Parvoviridae Infections, Pregnancy, Procedure-related complications, Humans, Perinatal Mortality, Alloimmunization, Intrauterine blood transfusion, Fetomaternal hemorrhage, Infant, Newborn, Fetal anemia, Perinatal outcome, Anemia, Fetofetal Transfusion, Fetomaternal Transfusion, Fetal Diseases, Treatment Outcome, Sacrococcygeal teratoma, Female

  • BIP!
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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    142
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
142
Top 1%
Top 10%
Top 10%
bronze