Background and Aims. This research investigates spatial and temporal trends in budburst timing across Australian wine regions from 1910–2019. The potential drivers of these observed trends were then identified, including anthropogenic climate change and large-scale climate drivers (El Nino–Southern Oscillation (ENSO), Indian Ocean Dipole (IOD), and Southern Annular Mode (SAM)). Methods and Results. The timing of budburst was approximated using accumulation measurements applied to Australia wide gridded temperature data. We show that the modelled budburst date has been gradually shifting to earlier in the year for most (95%) Australian wine regions, at an average rate of one day every 24 years. This linear trend in budburst timing is likely to be associated with steadily increasing air temperatures due to anthropogenic climate change. Significant interannual variability was also observed and was correlated with IOD and SAM; however, no significant relationship was found with ENSO. Positive IOD phases result in budburst occurring on average four days earlier than the long-term average; however, this can be as high as eight days. Conclusions. The results of this study highlight that budburst timing for wine grapes is not a stationary phenomenon and is influenced by both natural and anthropogenic conditions. Significance of the Study. Understanding variability and trends in modelled budburst timing will assist tactical and strategic management practices and improve phenological modelling and adaptation planning for climate change.