Intercellular Communication in Atherosclerosis

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2009 Switzerland English Publisher:American Physiological SocietyJournal:Physiology, volume 24, pages 36-44 (issn: 1548-9213, eissn: 1548-9221,

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Authors: Burnier, Laurent; Fontana, Pierre; Angelillo-Scherrer, Anne; Kwak, Brenda;

doi: 10.1152/physiol.00036.2008

pmid: 19196650

Intercellular Communication in Atherosclerosis

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Abstract

Cell-to-cell communication is a process necessary for physiological tissue homeostasis and appears often altered during disease. Gap junction channels, formed by connexins, allow the direct intercellular communication between adjacent cells. After a brief review of the pathophysiology of atherosclerosis, we will discuss the role of connexins throughout the different stages of the disease.

Country

Switzerland

Related Organizations

University of Geneva
Switzerland
University of Lausanne
Switzerland
University Hospital of Geneva
Switzerland
University Hospital of Lausanne
Switzerland

Keywords

Connexins / genetics, Gap Junctions / metabolism, Endothelium, Vascular / metabolism, Blood Vessels / metabolism, Gap Junctions, Cell Communication, 616.07, Blood Vessels / pathology, Atherosclerosis, Atherosclerosis / physiopathology, Connexins, Connexins / metabolism, Endothelium, Vascular / pathology, Atherosclerosis / pathology, Gap Junctions / pathology, Atherosclerosis / metabolism, 616, Animals, Blood Vessels, Humans, Endothelium, Vascular

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