descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2017 English Publisher:American Physiological SocietyJournal:Physiology, volume 32, pages 332-342 (issn: 1548-9213, eissn: 1548-9221,

Authors: Mohamed, Trebak; James W, Putney;

doi: 10.1152/physiol.00011.2017

pmid: 28615316

pmc: PMC5545608

ORAI Calcium Channels

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Abstract

In this review article, we discuss the different gene products and translational variants of ORAI proteins and their contribution to the makeup of different native calcium-conducting channels with distinct compositions and modes of activation. We also review the different modes of regulation of these distinct calcium channels and their impact on downstream cellular signaling controlling important physiological functions.

Related Organizations

National Institute of Health
Pakistan
National Institutes of Health
United States
Pennsylvania State University
United States
National Institute of Environmental Health Sciences
United States

Keywords

Animals, Humans, Calcium, Calcium Channels, Calcium Signaling

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