In this article, we introduce a cache-oblivious method for sparse matrix–vector multiplication. Our method attempts to permute the rows and columns of the input matrix using a recursive hypergraph-based sparse matrix partitioning scheme so that the resulting matrix induces cache-friendly behavior during sparse matrix–vector multiplication. Matrices are assumed to be stored in row-major format, by means of the compressed row storage (CRS) or its variants incremental CRS and zig-zag CRS. The zig-zag CRS data structure is shown to fit well with the hypergraph metric used in partitioning sparse matrices for the purpose of parallel computation. The separated block-diagonal (SBD) form is shown to be the appropriate matrix structure for cache enhancement. We have implemented a run-time cache simulation library enabling us to analyze cache behavior for arbitrary matrices and arbitrary cache properties during matrix–vector multiplication within a k-way set-associative idealized cache model. The results of these simulations are then verified by actual experiments run on various cache architectures. In all these experiments, we use the Mondriaan sparse matrix partitioner in one-dimensional mode. The savings in computation time achieved by our matrix reorderings reach up to 50 percent, in the case of a large link matrix.