Effects of a modified live CSFV vaccine on the development of PMWS in pigs infected experimentally with PCV‐2
Copyright policy )Effects of a modified live CSFV vaccine on the development of PMWS in pigs infected experimentally with PCV‐2
The objective of this study was to determine the effect of vaccination against classical swine fever virus (CSFV) on the development of postweaning multisystemic wasting syndrome (PMWS) in conventional pigs infected experimentally with porcine circovirus type 2 (PCV‐2). The pigs infected with PCV‐2 and immunised with modified live CSFV developed mild to moderate PMWS, whereas none of the pigs infected with PCV‐2 alone or immunised with modified live CSFV alone developed PMWS. Lesions histologically characteristic of PMWS were observed in lymph nodes from the pigs infected with PCV‐2 and immunised with modified live CSFV vaccine, and extensive replication of PCV‐2 was detected in the nodes by in situ hybridisation.
- Seoul National University, College of Veterinary Medicine Korea (Republic of)
- New Generation University College Ethiopia
- Seoul National University Korea (Republic of)
- SEOUL NATIONAL UNIVERSITY
- Seoul National University
Circovirus, Korea, Swine, Viral Vaccines, Disease Models, Animal, Porcine Postweaning Multisystemic Wasting Syndrome, Random Allocation, Classical Swine Fever Virus, Animals, Lymph Nodes, Circoviridae Infections, In Situ Hybridization
Circovirus, Korea, Swine, Viral Vaccines, Disease Models, Animal, Porcine Postweaning Multisystemic Wasting Syndrome, Random Allocation, Classical Swine Fever Virus, Animals, Lymph Nodes, Circoviridae Infections, In Situ Hybridization
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