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British Journal of Ophthalmology
Article . 2006 . Peer-reviewed
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Evolving European guidance on the medical management of neovascular age related macular degeneration

Authors: Chakravdrthy, U.; Soubrane, G.; Bandello, F.; Chong, V.; Creuzot garcher, C.; Dimitrakos Ii, S. A.; Korobelnik, J. . F.; +7 Authors

Evolving European guidance on the medical management of neovascular age related macular degeneration

Abstract

Until recently, only two options were available for the treatment of choroidal neovascularisation (CNV) associated with age related macular degeneration (AMD)-thermal laser photocoagulation and photodynamic therapy with verteporfin (PDT-V). However, new treatments for CNV are in development, and data from phase III clinical trials of some of these pharmacological interventions are now available. In light of these new data, expert guidance is required to enable retina specialists with expertise in the management of AMD to select and use the most appropriate therapies for the treatment of neovascular AMD.Consensus from a round table of European retina specialists was obtained based on best available scientific data. Data rated at evidence levels 1 and 2 were evaluated for laser photocoagulation, PDT-V, pegaptanib sodium, and ranibizumab. Other treatments discussed are anecortave acetate, triamcinolone acetonide, bevacizumab, rostaporfin (SnET2), squalamine, and transpupillary thermotherapy.PDT-V is currently recommended for subfoveal lesions with predominantly classic CNV, or with occult with no classic CNV with evidence of recent disease progression and a lesion size

Countries
United Kingdom, United Kingdom, Italy
Keywords

macular degeneration, Evidence-Based Medicine, name=Ophthalmology, 610, Antibodies, Monoclonal, Aptamers, Nucleotide, Antibodies, Monoclonal, Humanized, Triamcinolone Acetonide, Choroidal Neovascularization, Macular Degeneration, /dk/atira/pure/subjectarea/asjc/2700/2731, Treatment Outcome, Photochemotherapy, Ranibizumab, 616, Humans, Pregnadienediols

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    70
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
70
Top 10%
Top 10%
Top 1%
Green
bronze