Producing safe food, all the time, must be a foundational goal for any individual or corporation in the business of making food. It is critical to understand the risks associated with food and take actions to mitigate those risks. Food safety management systems (FSMSs) include multiple, interrelated elements to help ensure that risks are mitigated to an acceptable level. Good manufacturing practices and hazard analysis and critical control point (HACCP) programs are key elements of an FSMS, but there are other elements based in policy and culture that are also important. A robust FSMS that is effectively implemented, continuously monitored, verified, and subject to continuous improvement is essential for the success of food manufacturers.