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Prosaposin mediates inflammation in atherosclerosis

descriptionPublicationkeyboard_double_arrow_right Article 10 Mar 2021 Netherlands Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Translational Medicine, volume 13 (issn: 1946-6234, eissn: 1946-6242,

Authors: Yu-Xiang Ye; Emma D. Klein; Francois Fay; Francois Fay; Mihai G. Netea; Mihai G. Netea; Filip K. Swirski; +36 Authors

doi: 10.1126/scitranslmed.abe1433

pmid: 33692130

pmc: PMC8209679

handle: https://repository.ubn.ru.nl/handle/2066/231957 , 2066/231957

Prosaposin mediates inflammation in atherosclerosis

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Abstract

Prosaposin mediates inflammation in experimental and human atherosclerosis and is associated with cellular metabolism and mTOR signaling.

Country

Netherlands

Related Organizations

Ludwig-Maximilians-Universität München
Germany
Spanish National Centre for Cardiovascular Research
Spain
University of Chicago
United States
French National Centre for Scientific Research
France
Utrecht University
Netherlands

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Keywords

Radboudumc 16: Vascular damage RIMLS: Radboud Institute for Molecular Life Sciences, Radboudumc 4: lnfectious Diseases and Global Health RIMLS: Radboud Institute for Molecular Life Sciences, Inflammation, Mice, Knockout, ApoE, Nephrology - Radboud University Medical Center, Radboud University Medical Center, General Medicine, Radboudumc 11: Renal disorders RIMLS: Radboud Institute for Molecular Life Sciences, Atherosclerosis, Plaque, Atherosclerotic, Saposins, Mice, Inbred C57BL, Disease Models, Animal, Mice, Journal Article, Animals, Internal Medicine - Radboud University Medical Center

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	72
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 1%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 1%