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Science
Article . 2017
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Transgenerational transmission of environmental information in C. elegans

Authors: Adam Klosin; Eduard Casas; Cristina Hidalgo-Carcedo; Tanya Vavouri; Ben Lehner;

Transgenerational transmission of environmental information in C. elegans

Abstract

Ancestral legacy effects Environmental change can critically affect the lifestyle, reproductive success, and life span of adult animals and their for generations. Klosin et al. showed that in the nematode worm Caenorhabditis elegans , exposure to high temperatures led to expression of endogenously repressed copies of genes—sometimes called “junk” DNA. This effect persisted for >10 generations of worms. The changes in chromatin occurred in the early embryo before the onset of transcription and were inherited through eggs and sperm. Science , this issue p. 320

Country
Spain
Keywords

Male, Hot Temperature, Transcription, Genetic, Zygote, Medi ambient, Environment, Methylation, Epigenesis, Genetic, Histones, Heterochromatin, Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Oligonucleotide Array Sequence Analysis, Environmental Biomarkers, Lysine, Histone-Lysine N-Methyltransferase, Epigenètica, Spermatozoa, Oocytes, Female

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    417
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 0.1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 0.1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
417
Top 0.1%
Top 1%
Top 0.1%
Green