Serial Femtosecond Crystallography of G Protein–Coupled Receptors
Copyright policy )NIH| GPCR Network ,
EC| XLASERS ,
NIH| Prokaryotic Expression ,
NIH| Center for Membrane Proteins in Infectious Diseases (MPID) ,
NIH| JCIMPT-Complexes ,
SFI| Structure-Function Studies of Membrane Proteins Involved in Quorum Sensing and the Pathogencitcy of Pseudomonas aeruginosa ,
SFI| Membrane Structural and Functional Biology: Tackling communicable and non-communicable diseases at the membrane level. ,
NSF| Biology with X-ray Lasers ,
NIH| Femtosecond nano-crystallography of membrane proteins
W. Liu; D. Wacker; C. Gati; G. W. Han; D. James; D. Wang; G. Nelson; U. Weierstall; V. Katritch; A. Barty; N. A. Zatsepin; D. Li; M. Messerschmidt; S. Boutet; G. J. Williams; J. E. Koglin; M. M. Seibert; C. Wang; S. T. A. Shah; S. Basu; R. Fromme; C. Kupitz; K. N. Rendek; I. Grotjohann; P. Fromme; R. A. Kirian; K. R. Beyerlein; T. A. White; H. N. Chapman; M. Caffrey; J. C. H. Spence; R. C. Stevens; V. Cherezov;
Serial Femtosecond Crystallography of G Protein–Coupled Receptors
G Structures G protein–coupled receptors (GPCRs) are eukaryotic membrane proteins that have a central role in cellular communication and have become key drug targets. To overcome the difficulties of growing GPCRs crystals, Liu et al. (p. 1521 ) used an x-ray free-electron laser to determine a high-resolution structure of the serotonin receptor from microcrystals.
Germany
- SLAC National Accelerator Laboratory United States
- Uppsala University Sweden
- Helmholtz Association of German Research Centres Germany
- Deutsches Elektronen-Synchrotron DESY Germany
- UNIVERSITY OF HAMBURG Germany
Time Factors, Protein Conformation, Lasers, Receptor, Serotonin, 5-HT2B, Humans, Crystallography, X-Ray, info:eu-repo/classification/ddc/500, Receptors, G-Protein-Coupled
Time Factors, Protein Conformation, Lasers, Receptor, Serotonin, 5-HT2B, Humans, Crystallography, X-Ray, info:eu-repo/classification/ddc/500, Receptors, G-Protein-Coupled
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selected citations
Citations provided by BIP!
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 419
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