Emergence of Lineage IV Peste des Petits Ruminants Virus in Ethiopia: Complete Genome Sequence of an Ethiopian Isolate 2010
Copyright policy )Emergence of Lineage IV Peste des Petits Ruminants Virus in Ethiopia: Complete Genome Sequence of an Ethiopian Isolate 2010
Isolates of peste des petits ruminants virus (PPRV) can be segregated genetically into four lineages. For decades, lineages I-III have been reported across Africa whilst lineage IV has predominantly circulated across Asia. However, the lineage distribution is currently changing in Africa. Importantly, full genome sequence data for African field isolates have been lacking. Here, we announce the first complete genome sequence of a field isolate of peste des petits ruminants virus (PPRV) from East Africa. This isolate was derived from the intestine of a goat suffering from severe clinical disease during the 2010 outbreak in Ethiopia. The full genome sequence of this isolate, PPRV Ethiopia/2010, clusters genetically with other lineage IV isolates of PPRV, sharing high levels of sequence identity across the genome. Further, we have carried out a phylogenetic analysis of all of the available African partial N gene and F gene PPRV sequences to investigate the epidemiology of PPRV with a focus on the emergence of different lineages of PPRV in Africa.
- Lancaster University United Kingdom
- Centre de Coopération Internationale en Recherche Agronomique pour le Développement France
- Département Sciences sociales, agriculture et alimentation, espace et environnement France
- Animal and Plant Health Agency United Kingdom
- National Veterinary Institute Ethiopia
570, chèvre, http://aims.fao.org/aos/agrovoc/c_2615, Biodiversité et Ecologie, http://aims.fao.org/aos/agrovoc/c_16581, pourcentage d'identite de séquences, virus, Genome, Viral, L73 - Maladies des animaux, 630, virus peste petits ruminants, Peste-des-petits-ruminants virus, Biodiversity and Ecology, lignée, séquençage, Peste-des-Petits-Ruminants, phylogénie, Animals, http://aims.fao.org/aos/agrovoc/c_2676, http://aims.fao.org/aos/agrovoc/c_3224, http://aims.fao.org/aos/agrovoc/c_13325, http://aims.fao.org/aos/agrovoc/c_5066, Phylogeny, http://aims.fao.org/aos/agrovoc/c_29225, phylogenetic analysis, génome, peste des petits ruminants;lineage;epidemiology;genome sequencing;phylogenetic analysis, http://aims.fao.org/aos/agrovoc/c_27583, afrique, asie, 600, Sequence Analysis, DNA, séquence nucléotidique, peste, peste des petits ruminants, genome sequencing, [SDE.BE] Environmental Sciences/Biodiversity and Ecology, séquence du génome, épidémiologie, epidemiology, Ethiopia, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, http://aims.fao.org/aos/agrovoc/c_2442, http://aims.fao.org/aos/agrovoc/c_16789, lineage
570, chèvre, http://aims.fao.org/aos/agrovoc/c_2615, Biodiversité et Ecologie, http://aims.fao.org/aos/agrovoc/c_16581, pourcentage d'identite de séquences, virus, Genome, Viral, L73 - Maladies des animaux, 630, virus peste petits ruminants, Peste-des-petits-ruminants virus, Biodiversity and Ecology, lignée, séquençage, Peste-des-Petits-Ruminants, phylogénie, Animals, http://aims.fao.org/aos/agrovoc/c_2676, http://aims.fao.org/aos/agrovoc/c_3224, http://aims.fao.org/aos/agrovoc/c_13325, http://aims.fao.org/aos/agrovoc/c_5066, Phylogeny, http://aims.fao.org/aos/agrovoc/c_29225, phylogenetic analysis, génome, peste des petits ruminants;lineage;epidemiology;genome sequencing;phylogenetic analysis, http://aims.fao.org/aos/agrovoc/c_27583, afrique, asie, 600, Sequence Analysis, DNA, séquence nucléotidique, peste, peste des petits ruminants, genome sequencing, [SDE.BE] Environmental Sciences/Biodiversity and Ecology, séquence du génome, épidémiologie, epidemiology, Ethiopia, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, http://aims.fao.org/aos/agrovoc/c_2442, http://aims.fao.org/aos/agrovoc/c_16789, lineage
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