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Journal of the Royal Statistical Society Series A (Statistics in Society)
Article . 2020 . Peer-reviewed
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https://dx.doi.org/10.48550/ar...
Article . 2019
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Selecting a Scale for Spatial Confounding Adjustment

Selecting a scale for spatial confounding adjustment
Authors: Keller, Joshua P.; Szpiro, Adam A.;

Selecting a Scale for Spatial Confounding Adjustment

Abstract

SummaryUnmeasured, spatially structured factors can confound associations between spatial environmental exposures and health outcomes. Adding flexible splines to a regression model is a simple approach for spatial confounding adjustment, but the spline degrees of freedom do not provide an easily interpretable spatial scale. We describe a method for quantifying the extent of spatial confounding adjustment in terms of the Euclidean distance at which variation is removed. We develop this approach for confounding adjustment with splines and using Fourier and wavelet filtering. We demonstrate differences in the spatial scales that these bases can represent and provide a comparison of methods for selecting the amount of confounding adjustment. We find the best performance for selecting the amount of adjustment by using an information criterion evaluated on an outcome model without exposure. We apply this method to spatial adjustment in an analysis of fine particulate matter and blood pressure in a cohort of US women.

Keywords

FOS: Computer and information sciences, spatial filtering, regression splines, Applications of statistics, Statistics - Applications, confounding, air pollution epidemiology, Methodology (stat.ME), Applications (stat.AP), Statistics - Methodology

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    30
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
30
Top 10%
Top 10%
Top 10%
Green
hybrid