Vemurafenib‐Induced Neutrophilic Panniculitis in a Child with a Brainstem Glioma

descriptionPublicationkeyboard_double_arrow_right Article 06 Mar 2014 English Publisher:WileyJournal:Pediatric Dermatology, volume 32, pages 153-154 (issn: 0736-8046, eissn: 1525-1470,

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Authors: Emily S, West; Victoria L, Williams; Joseph G, Morelli;

doi: 10.1111/pde.12316

pmid: 24602192

Vemurafenib‐Induced Neutrophilic Panniculitis in a Child with a Brainstem Glioma

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Abstract

AbstractNeutrophilic panniculitis is a rare adverse effect of therapy with selective BRAF inhibitors. We report a case of neutrophilic panniculitis in a 15‐year‐old girl receiving treatment with vemurafenib for a brainstem glioma. Clinicians should be aware of this rare but important side effect of vemurafenib. This is the first report of neutrophilic panniculitis in a child treated with vemurafenib.

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Keywords

Proto-Oncogene Proteins B-raf, Sulfonamides, Indoles, Panniculitis, Adolescent, Neutrophils, Antineoplastic Agents, Glioma, Vemurafenib, Brain Stem Neoplasms, Humans, Female

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