Eighteen fungi isolated from soil by hair bating method were tested against soil inhabiting Microsporum equinum, Microsporum fulvum, Microsporum gypseum and Microsporum racemosum for their antagonistic interactions. Colony inhibition during dual cultures showed inhibition of all the four Microsporum species. The maximum inhibition of M. equinum, M. fulvum, M. gypseum and M. racemosum was caused by Chrysosporium keratinophilum, Chrysosporium tropicum, Curvularia lunata and Chrysosporium lucknowense in dual cultures. On the other hand, M. fulvum showed maximum inhibition of Macrophomina phaseolina (70.1%) while M. equinum, M. gypseum and M. racemosum showed maximum inhibition of Colletotrichum gloeosporoides. Staling products of C. lucknowense accelerated growth of all Microsporum species, C. keratinophilum 3 and Chrysosporium evolceaunui and M. phaseolina accelerated growth of two species of Microsporum. Staling product of Alternaria alternata was most inhibitory. Culture filtrates of Trichophyton vanbreseughemii accelerated the growth of all the four Microsporum species and C. tropicum, C. lucknowense accelerated growth of two species, while Botryotrichum piluliferum accelerated growth of three species of Microsporum. Volatiles showed inhibition of all the Microsporum species ranging from 0.33 to 57.2% except in case of M. fulvum. Lysis of Microsporum mycelium was the most common feature.