Quiescent melanocytes form primary cilia

descriptionPublicationkeyboard_double_arrow_right Article 28 May 2014 English Publisher:WileyJournal:Experimental Dermatology, volume 23, pages 426-427 (issn: 0906-6705, eissn: 1600-0625,

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Authors: Madeleine, Le Coz; Alexandre, Benmerah; Lionel, Larue;

doi: 10.1111/exd.12426

pmid: 24758532

Quiescent melanocytes form primary cilia

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Abstract

AbstractWe show, for the first time, that melanocytes can form a primary cilium in vitro, corresponding to an immotile or sensory cilium. Such cilia are observed when melanocytes reach confluence or when medium nutrient levels are insufficient. This observation should greatly improve our understanding of the signal transduction processes potentially occurring in these cells during embryonic development, homeostasis in adulthood and melanomagenesis.

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Keywords

In Vitro Techniques, Cell Line, Mice, Animals, Humans, Melanocytes, Cilia, Cells, Cultured, Cellular Senescence, Cell Proliferation, Signal Transduction

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