Harmonized regulation of invertebrate biological control agents (IBCAs) is a major challenge for the 51 countries of the European and Mediterranean Plant Protection Organization (EPPO). Although some of these member countries in the EPPO region have well‐defined regulations and follow a common approach, others do not. The North American Plant Protection Organization (NAPPO) has achieved a common approach in North America through the development of Regional Standards for Phytosanitary Measures specific to IBCAs that outline the information required for submission of a request to release an agent. NAPPO has also developed a process to ensure that submissions are reviewed by experts and regulatory officials in all three member countries. It is proposed that EPPO takes advantage of the experience of NAPPO in developing a harmonized approach for regulating IBCAs.