ABSTRACTThis article explores some of the consequences of open access (OA) for scholars in the global South, centring on what constitutes their equal participation in the global circuit of knowledge production. Building on critical reflections by contributors to the ‘Power Shifts’ project within the From Poverty to Power blog, the limitations of the OA model are shown to be tied to a series of structural features characteristic of the twin systems of academic research and publishing. What the challenges faced by many scholars in the global South demonstrate is that ‘openness’, or inclusion in this format, is not yet the guarantee for equality that many had hoped. The article frames this as a systemic knowledge issue at a global scale that cannot be remedied by a simple reform to academic publishing. The article points to some creative efforts by scholars to forge alternative models for scholarly communication that move away from a marketized and restrictive model of knowledge production, and towards epistemic justice. The authors conclude that while OA represents a positive step forward in making knowledge a public good, it is no substitute for a more comprehensive rethink to pluralize our ways of knowing.