The limited success reported in the paralarval culture of merobenthic octopus is mainly attributed to nutritional problems. This study aimed to determine the effect of live diets on the paralarvae performance during the first 30 days after hatching (DAH). The paralarvae were grown under different treatments: starved (STV) as negative control or fed four diets: Artemia sp. enriched with microalgae (ANCH), Artemia enriched with a commercial enrichment (AOG), Artemia enriched with microalga + commercial enrichment (AMIX) and king crab zoea (ZKC). The paralarval growth and survival were affected by the dietary treatment, with significant higher growth in ANCH and AMIX. STV showed 100% mortality at day 27, whereas all diets resulted within a range from 20% to 33% survival. The endogenous protein and lipid reserves were utilized in all treatments. The 22:6n-3/20:5n-3 ratio increased up to 16% during the experimental period. Alkaline protease activity tended to increase in paralarvae fed ANCH, AOG and ZKC over the first 13 DAH; however, this effect was not observed in trypsin nor chymotrypsin activities. The leucine aminopeptidase activity (LAP) was not affected by the dietary treatment, while alkaline phosphatases increased only at 13 DAH in paralarvae fed ANCH. Indicators of the nutritional status of paralarvae are discussed.