In the present paper, we present our approach for the transformation of workflow applications based on institution theory. The workflow application is modeled with UML Activity Diagram(UML AD). Then, for a formal verification purposes, the graphical model will be translated to an Event-B specification. Institution theory will be used in two levels. First, we defined a local semantic for UML AD and Event B specification using a categorical description of each one. Second, we defined institution comorphism to link the two defined institutions. The theoretical foundations of our approach will be studied in the same mathematical framework since the use of institution theory. The resulted Event-B specification, after applying the transformation approach, will be used for the formal verification of functional proprieties and the verification of absences of problems such deadlock. Additionally, with the institution comorphism, we define a semantic correctness and coherence of the model transformation.