Semantic computing is an emerging research field that has drawn much attention from both academia and industry. It addresses the derivation and matching of semantics of computational "contents" where "contents" may be anything including text, multimedia, hardware, network, etc. which can be mapped to many areas in computer science that involve analyzing and processing the intension of humans with computational content. This paper discusses some potential applications of Semantic Computing in Computer Science. We examine semantic analytical techniques as applied for primary sequence analysis for genes and proteins in biomedical area. We also introduce how privacy and confidentiality problems are resolved, while the query from a user are written in natural language.