In this paper, we present the closed-form models of conductor thickness dependent dispersive line parameters and losses, of multilayer coplanar stripline (CPS) on isotropic dielectric substrates. The dispersive empirical expressions for the single-layer CPS from literature are improved to include the finite conductivity and finite conductor thickness in propagation characteristics and losses. The single layer reduction (SLR) formulation of lossy multilayer CPS is then used to extend the closed-form models developed for computation of line parameters, to multilayer structures. All developed models are verified against the results obtained using the EM-simulators for frequency range 1 GHz–60 GHz over wide range of parameters.