Index modulation assisted OFDM (OFDM-IM) has become a popular technique in wireless communications. In this paper, we proposes a novel multilayer framework for OFDM-IM. Being quite generic in its nature, the framework can be amalgamated with most of the OFDM-IM variants. For coherent OFDM-IM, we propose three different schemes; 1) multilayer index modulation (MIM); 2) dual mode MIM; and 3) compressive sampling aided MIM. The schemes strikes a compelling tradeoff between the BER, energy efficiency and throughput. Finally, we extend this multilayer framework to non-coherent index modulation, where the structure provides an improved BER performance compared to its single layer counterpart, albeit this is achieved at the cost of reduced energy efficiency. The performance analysis of the proposed scheme is confirmed by our simulation results.