
A simple zipper model is introduced, representing in a simplified way, e.g., the folded DNA double helix or hairpin structures in RNA. The double stranded hairpin is connected to a heat bath at temperature T and subject to an external force f, which couples to the free length L of the unzipped sequence. The leftmost zipped position can be seen as the position of a random walker in a special external field. Increasing the force leads to a zipping-unzipping first-order phase transition at a critical force f_{c}(T) in the thermodynamic limit of a very large chain. We compute analytically, as a function of temperature T and force f, the full distribution P(L) of free lengths in the thermodynamic limit and show that it is qualitatively very different for ff_{c}. Next we consider quasistatic work processes where the force is incremented according to a linear protocol. Having obtained P(L) already allows us to derive an analytical expression for the work distribution P(W) in the zipped phase f
Physics - Biological Physics, Physics - Computational Physics, Condensed Matter - Statistical Mechanics
Physics - Biological Physics, Physics - Computational Physics, Condensed Matter - Statistical Mechanics
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