In this paper experiments a r e reported on annihilation and scattering of antiprotons in H{sub 2}O , D{sub 2}O, and O{sub 2}. From the data measured i t i s possible to obtain an antiproton-proton and a n antiproton-deuteron c r o s s section a t 457 Mev (lab). Further analysis gives the p-p and p-n c r o s s sections a s 104 mb for the H-p reaction c r o s s section and 113 mb for the p-n reaction c r o s s section. The respective annihilation cross sections a r e 89 and 74 mb. The Glauber correction necessary in order to pass from the p-d to the p-n c r o s s section by subtraction of the p-p c r o s s section i s unfortunately large and somewhat uncertain. The data a r e compared with the p-p and p-n c r o s s sections and with other results on p - p collisions.