The anatomical connections of the orbitofrontal cortex are described. The orbitofrontal cortex receives from the end of every sensory hierarchy information about what taste, smell, touch, visual stimulus including objects and faces, and what auditory stimuli including vocalization, is present. There are major outputs of the orbitofrontal cortex to the cingulate cortex, striatum, inferior frontal gyrus, and indirectly including via the habenula to the dopamine and serotonin neurons in the brainstem.

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