Entrapment neuropathy is caused by compression, angulation, or stretch of a peripheral nerve as it passes through a fibro-osseous canal such as the carpal or the cubital tunnel (in the case of the median or the ulnar nerves). In addition to true entrapment neuropathies, individual nerves can be injured at vulnerable anatomical locations such as the fibular head (in case of the fibular nerve). Pregnancy causes a variety of physiological changes related to reproductive hormone secretion that can affect peripheral nerve. These include weight gain, salt and water retention, edema and hyperglycemia.1 Two entrapment neuropathies that occur commonly in pregnancy are carpal tunnel syndrome and meralgia paresthetica.2 In addition to these true entrapment neuropathies, this chapter addresses other common focal mononeuropathies: femoral, obturator, and fibular neuropathies that may occur as a consequence of obstetrical procedures or of fetal or maternal positioning during delivery or in the postpartum period.