Background: Interactive voice response (IVR) systems are computer programs that interact with people to provide a number of services from business to healthcare. The healthcare applications are particularly relevant to older adults because they are important consumers of medical services. However, research has found that older adults can experience significant difficulties with IVR and have more negative attitudes toward the technology. Subjects and Methods: Seniors' attitudes appear to be related to their most recent experiences with IVR systems. The objective of this study was to examine attitudes toward four commercial or governmental IVR systems and how these attitudes relate to participants' ability to interact with the technology in a sample of 185 community-dwelling older (>65-year-old) adults. We also examined the effects of several demographic factors on both success and attitudes toward automated systems. Results: We found a significant positive correlation between IVR success and attitudes toward IVR. However, a large subset of our sample gave high ratings despite experiencing significant difficulties with the systems. These participants tended to have lower full scale IQ. No gender differences emerged in terms of attitudes and ability to interact with IVR systems. Conclusions: Results also indicated that older adults in our sample viewed the IVR interaction as particularly demanding on attention and concentration abilities.