Colistin- and Carbapenem-Resistant  Klebsiella pneumoniae  Clinical_Isolates: Algeria

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2019 France English Publisher:SAGE PublicationsJournal:Microbial Drug Resistance, volume 25, pages 258-263 (issn: 1076-6294, eissn: 1931-8448,

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Authors: Yousfi, Hanane; Hadjadj, Linda; Dandachi, Iman; Lalaoui, Rym; Merah, Adil; Amoura, Kamel; Dahi, Ahlem; +5 Authors

doi: 10.1089/mdr.2018.0147

pmid: 30256174

Colistin- and Carbapenem-Resistant Klebsiella pneumoniae Clinical_Isolates: Algeria

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Abstract

This study investigates the molecular mechanisms of colistin and carbapenem resistance in Klebsiella pneumoniae ST101 strains. The three K. pneumoniae carried bla CTX-M-15 , bla TEM-183 , and bla SHV-106 genes and two coharbored bla OXA-48 . As for colistin resistance, the isolates had amino acid substitutions in PmrA/B and a truncated mgrB gene in one isolate.

Country

France

Related Organizations

Aix-Marseille University
France
Aix Marseille Université
France
University of Balamand
Lebanon
French National Centre for Scientific Research
France
Badji Mokhtar University
Algeria

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Keywords

Colistin, Microbial Sensitivity Tests, beta-Lactamases, Anti-Bacterial Agents, Klebsiella Infections, Klebsiella pneumoniae, Amino Acid Substitution, Carbapenems, Algeria, Drug Resistance, Bacterial, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Humans

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