Inadequate life-history information can compromise management of shark populations. The present study examined the life history of blacktip reef sharks (Carcharhinus melanopterus) from north-eastern Australia with predictions that they would show life-history patterns similar to those of other reef sharks species. Age and growth estimates were derived from vertebrae and five growth models. Males were 543–1390 mm total length (LST) and females were 514–1600 mm LST. Longevity was 10 years (males) and 15 years (females). Chemical marking confirmed annual band pair deposition but indicated probable age underestimation of large individuals. The logistic model was preferred (second-order Akaike information criterion (AICc) weight 0.7536), with growth parameter estimates of length at birth (L0) = 617 mm LST; asymptotic length (L8) = 1585 mm LST; k (from logistic model) = 0.251 year–1. Males matured at 4.2 years (1050 mm LST) and females at 8.5 years (1335 mm LST), although further verification is needed. Mating and parturition occurred in summer and autumn, females having three or four pups per litter. Data were inconclusive in determining reproductive periodicity. These data contribute to the species management and conservation and suggest that the species may be sensitive to fishing pressure and habitat loss. The study also demonstrated potential complications in using vertebrae to estimate age and growth of chondrichthyan fishes.