Johne's disease (paratuberculosis) afflicts cattle worldwide and causes significant economic losses. It is also prevalent in goats and sheep and has been implicated in Johne's disease in humans. The book is divided into six sections covering all aspects of the prevalence, management, diagnosis, control and research on Johne's disease. ]ohne's disease is an international animal health problem, and is of particular importance in the southern States of Australia, especially in the major dairy areas of Victoria where approximately 10% of dairy herds are infected.