The quality of bathymetric and topographic resolution significantly affect the accuracy of tsunami run-up and inundation simulation. However, high resolution gridded bathymetric and topographic data sets for Malaysia are not freely available online. It is desirable to have seamless integration of high resolution bathymetric and topographic data. The bathymetric data available from the National Hydrographic Centre (NHC) of the Royal Malaysian Navy are in scattered form; while the topographic data from the Department of Survey and Mapping Malaysia (JUPEM) are given in regularly spaced grid systems. Hence, interpolation is required to integrate the bathymetric and topographic data into regularly-spaced grid systems for tsunami simulation. The objective of this research is to analyze the most suitable interpolation methods for integrating bathymetric and topographic data with minimal errors. We analyze four commonly used interpolation methods for generating gridded topographic and bathymetric surfaces, namely (i) Kriging, (ii) Multiquadric (MQ), (iii) Thin Plate Spline (TPS) and (iv) Inverse Distance to Power (IDP). Based upon the bathymetric and topographic data for the southern part of Penang Island, our study concluded, via qualitative visual comparison and Root Mean Square Error (RMSE) assessment, that the Kriging interpolation method produces an interpolated bathymetric and topographic surface that best approximate the admiralty nautical chart of south Penang Island.