Betulenols from Betula Species

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2000 Turkey Publisher:Georg Thieme Verlag KGJournal:Planta Medica, volume 66, pages 490-493 (issn: 0032-0943, eissn: 1439-0221,

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Authors: Demirci, Betül; Başer, K. Hüsnü Can; Özek, Temel; Demirci, Fatih;

doi: 10.1055/s-2000-8591

pmid: 10909279

handle: 11421/11771

Betulenols from Betula Species

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Abstract

The essential oils from buds of five Betula species growing in Turkey were investigated by GC-MS. A major component in the essential oils was shown to be 14-hydroxy-beta-caryophyllene (6). The structure of beta-betulenal (12) which was isolated from Betula essential oils was also confirmed by synthesis. Chemical reactions yielded 14-acetoxy-beta-caryophyllene (15), 14-hydroxy-isocaryophyllene (10) and its acetate (14), giving evidence to the natural occurrence in Betula species of the formerly known alpha-betulenol acetate (3), beta-betulenol (2) and beta-betulenol acetate (4), respectively. Compounds 6, 9, 10, 12, and 15 were evaluated for antimicrobial activity.

Country

Turkey

Related Organizations

Anadolu University
Turkey

Keywords

Plants, Medicinal, Turkey, Microbial Sensitivity Tests, Gram-Positive Bacteria, Gas Chromatography-Mass Spectrometry, Anti-Bacterial Agents, Bridged Bicyclo Compounds, Anti-Infective Agents, Oils, Volatile, Cyclobutanes, Gammaproteobacteria, Candida

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