What have our young patients eaten in the past 24 hours? Probably cooked, prepared, or even finely chopped foods, that require limited masticatory action compared to what our craniofacial muscles are used to.The impact of masticatory hypofunctioning on craniofacial muscle development has been discussed in paleoanthropology studies and experimental animal studies.Masticatory activity is one of the most frequently underestimated functions from both an etiopathogenic and therapeutic perspective in orthodontics. However, the recent development of prospective clinical studies allows for a complementary approach to the correlations between form and function and also allows us to examine the therapeutic importance of high masticatory stress.