In the article, 10 species of pests that damage rice plants during the season in the rice agrobiocenosis were identified. Leptestheria dahalacensis Sars, Apus concriformis Sh., Corn stalk Ostrinia nubilalis Hb, and Cephus pygmaeus have been reported to cause damage to rice grasses.A growth calendar has been developed. In the pest experiment during the rice germination period, biological effectiveness of the drug was the highest for 15 days, accounted for 93.9%, in the variant treated with Nurell D 55% em.k at rate of 1.5 l/ha. When the variant was treated with Tayshin 500 s.d.g (Clothianidin) at rate of 0.06 kg/ha, the effectives of the drug were 93.3% in 14 days. In the experiment, Nurell D 55% em.k (1.5 l/ha) was used against the main pests (0.06kg/ha) yielded 70.7 q/ha in the variant in which the chemical agent was used, and 10.1 additional yields were reported. The results showed that the yield of “Iskandar” variety was 73.8 q/ha, which was 13.2 q/ha more than the control, when Nurell D 55% em.k (1.5 l/ha) against the main pests was applied. Whereas new chemical Tayshin 500 s.d.g. (0.06kg/ha) was used in the variant, in which the yield was 70.7 q/ha, and it was more by 10.1 q/ha than the control variant.