Rapid electronic prediction of gene expression regulation in bacterial cells

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2014 English Publisher:Institution of Engineering and Technology (IET)Journal:Electronics Letters, volume 50, pages 1,566-1,568 (issn: 0013-5194, eissn: 1350-911X,

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Authors: S. Alam; E.M‐K. Lai; J. Young; S.M.R. Hasan;

doi: 10.1049/el.2014.2144

Rapid electronic prediction of gene expression regulation in bacterial cells

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Abstract

A cytomorphic circuit that can mimic gene expression regulation mechanisms is presented. It is shown that this circuit can efficiently predict the cellular response of the bacterium Escherichia coli in real time. The simulation outputs of the circuit are compared with biological experimental results. The significant similarity between these results shows that the circuit can be used to predict cellular malfunctioning within microseconds.

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