Immune cell activation produces locally scrambled foci of plasma membrane lipids
Copyright policy )NIH| Transient loss of plasma membrane asymmetry in mammalian cells: mechanisms and function ,
NIH| Mutual regulation between membrane rafts and protein condensates in T cell activation ,
NIH| Biophysical and functional coupling of protein condensates to ordered lipid domains in T-cells ,
NIH| The functional organization of mammalian membranes
Daryna Sputay; Milka Doktorova; Sze Ham Chan; Emma Han Guo; Hong-Yin Wang; Joseph H. Lorent; Ilya Levental; +1 Authors
Daryna Sputay; Milka Doktorova; Sze Ham Chan; Emma Han Guo; Hong-Yin Wang; Joseph H. Lorent; Ilya Levental; Kandice R. Levental;
Immune cell activation produces locally scrambled foci of plasma membrane lipids
We show that phosphatidylserine and phosphatidylethanolamine appear as transient foci on the plasma membrane external leaflet following immune receptor-mediated activation of mast cells.
Belgium
- University of Virginia United States
- Stockholm University Sweden
- UNIVERSITY OF VIRGINIA
- Université Catholique de Louvain Belgium
- UNIVERSITY OF VIRGINIA
Chemistry, Membrane Lipids, Mice, Phosphatidylethanolamines, T-Lymphocytes, Cell Membrane, Animals, Humans, Calcium, Phosphatidylserines, Mast Cells
Chemistry, Membrane Lipids, Mice, Phosphatidylethanolamines, T-Lymphocytes, Cell Membrane, Animals, Humans, Calcium, Phosphatidylserines, Mast Cells
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NIH| Transient loss of plasma membrane asymmetry in mammalian cells: mechanisms and function, NIH| Mutual regulation between membrane rafts and protein condensates in T cell activation, NIH| Biophysical and functional coupling of protein condensates to ordered lipid domains in T-cells, NIH| The functional organization of mammalian membranes
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