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Targeting SARS-CoV-2 spike protein by stapled hACE2 peptides

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2021 Denmark English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Communications, volume 57, pages 3,283-3,286 (issn: 1359-7345, eissn: 1364-548X, Copyright policy )Funded by:EC | ChemEpigen
Authors: Marijn N. Maas; Jordi C. J. Hintzen; Philipp M. G. Löffler; Jasmin Mecinović;

doi: 10.1039/d0cc08387a

pmid: 33651072

Targeting SARS-CoV-2 spike protein by stapled hACE2 peptides

Abstract

Stapled hACE2 peptides inhibit the formation of the SARS-CoV-2-hACE2 complex, providing the basis for the development of anti-COVID-19 therapeutics.

Country
Denmark
Related Organizations
Keywords

SARS-CoV-2, Spike Glycoprotein, Coronavirus, COVID-19, Humans, Amino Acid Sequence, Angiotensin-Converting Enzyme 2, Peptidomimetics, Peptides

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 42
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
42
Top 10%
Top 10%
Top 1%
Green
hybrid