
WO-Seq: a bisulfite-free and base-resolution sequencing method based on peroxotungstate oxidation is presented for the identification of hm5C sites in the transcriptome. Combining the peroxotungstate oxidation with TET enzyme oxidation, m5C can also be detected in a procedure termed TET-Assisted WO-Seq (TAWO-Seq).
Chemistry, Base Sequence, Sequence Analysis, RNA, RNA, Cytidine, Tungsten Compounds
Chemistry, Base Sequence, Sequence Analysis, RNA, RNA, Cytidine, Tungsten Compounds
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