Di-macrocyclic terephthalamide ligands as chelators for the PET radionuclide zirconium-89

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2015 English Publisher:Royal Society of Chemistry (RSC)Journal:Chemical Communications, volume 51, pages 2,301-2,303 (issn: 1359-7345, eissn: 1364-548X,

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Authors: Darpan N, Pandya; Sylvie, Pailloux; David, Tatum; Darren, Magda; Thaddeus J, Wadas;

doi: 10.1039/c4cc09256b

pmid: 25556851

pmc: PMC4507282

Di-macrocyclic terephthalamide ligands as chelators for the PET radionuclide zirconium-89

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Abstract

Octadentate terephthalamide ligands can be easily radiolabeled with 89Zr and are highly stable in vitro. They represent a novel class of bifunctional chelators for 89Zr.

Related Organizations

University of California, Davis
United States
Wake Forest University
United States
University of California, Berkeley
United States

Keywords

Phthalic Acids, Amides, Coordination Complexes, Isotope Labeling, Positron-Emission Tomography, Humans, Tissue Distribution, Zirconium, Radiopharmaceuticals, Chelating Agents, Half-Life

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