TBD-organocatalysed synthesis of pyrazolines

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2009 France English Publisher:Royal Society of Chemistry (RSC)Journal:Organic & Biomolecular Chemistry, volume 7, page 3,648 (issn: 1477-0520, eissn: 1477-0539,

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Authors: Mahé, Olivier; Frath, Denis; Dez, Isabelle; Marsais, Francis; Levacher, Vincent; Brière, Jean-François;

doi: 10.1039/b911577c

pmid: 19707665

TBD-organocatalysed synthesis of pyrazolines

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Abstract

It was found that TBD, a cheap and commercially available guanidine, easily catalysed the synthesis of biologically important 3,5-diarylpyrazolines from chalcones and acylhydrazines via a selective secondary amine alkylation.

Country

France

Related Organizations

Normandie Université
France
University of Caen Lower Normandy
France
University of Rouen
France
Centre national de la recherche scientifique
France
French National Centre for Scientific Research
France

Keywords

Hydrazines, Magnetic Resonance Spectroscopy, Alkylation, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Pyrazoles, Stereoisomerism, 540, Catalysis, Guanidine

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