
doi: 10.1039/b813860e
pmid: 19370239
We present a rapid prototyping method for integrating functional components in conventional PDMS microfluidic devices. We take advantage of stop-flow lithography (D. Dendukuri, S. S. Gu, D. C. Pregibon, T. A. Hatton and P. S. Doyle, Lab Chip, 2007, 7, 818)(1) to achieve the in situ fabrication of mobile and deformable elements with a controlled mechanical response. This strategy is applied to the fabrication of microflow sensors based on a deformable spring-like structure. We show that these sensors have a large dynamic range, typically 3 to 4 orders of magnitude, and that they can be scaled down to measure flows in the nl per min range. We prepared sensors with different geometries, and their flow-elongation characteristics were modeled with a simple hydrodynamic model, with good agreement between model and experiments.
Equipment Failure Analysis, Microchemistry, Transducers, Computer-Aided Design, Reproducibility of Results, Equipment Design, Microfluidic Analytical Techniques, Sensitivity and Specificity
Equipment Failure Analysis, Microchemistry, Transducers, Computer-Aided Design, Reproducibility of Results, Equipment Design, Microfluidic Analytical Techniques, Sensitivity and Specificity
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 48 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
