
pmid: 25419961
Force spectroscopy has become an indispensable tool to unravel the structural and mechanochemical properties of biomolecules. Here we extend the force spectroscopy toolbox with an acoustic manipulation device that can exert forces from subpiconewtons to hundreds of piconewtons on thousands of biomolecules in parallel, with submillisecond response time and inherent stability. This method can be readily integrated in lab-on-a-chip devices, allowing for cost-effective and massively parallel applications.
Spectrum Analysis, Microfluidics, Biophysics, Acoustics, DNA, Equipment Design, Biophysical Phenomena, Microspheres, Antigen-Antibody Reactions, DNA-Binding Proteins, Rec A Recombinases, Lab-On-A-Chip Devices, SDG 7 - Affordable and Clean Energy, Digoxigenin, Molecular Biology
Spectrum Analysis, Microfluidics, Biophysics, Acoustics, DNA, Equipment Design, Biophysical Phenomena, Microspheres, Antigen-Antibody Reactions, DNA-Binding Proteins, Rec A Recombinases, Lab-On-A-Chip Devices, SDG 7 - Affordable and Clean Energy, Digoxigenin, Molecular Biology
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