
doi: 10.1038/ng.736
pmid: 21186351
We sequenced and assembled the draft genome of Theobroma cacao, an economically important tropical-fruit tree crop that is the source of chocolate. This assembly corresponds to 76% of the estimated genome size and contains almost all previously described genes, with 82% of these genes anchored on the 10 T. cacao chromosomes. Analysis of this sequence information highlighted specific expansion of some gene families during evolution, for example, flavonoid-related genes. It also provides a major source of candidate genes for T. cacao improvement. Based on the inferred paleohistory of the T. cacao genome, we propose an evolutionary scenario whereby the ten T. cacao chromosomes were shaped from an ancestor through eleven chromosome fusions.
MESH: Cell Nucleus, 570, Genotype, MESH: Cacao, Quantitative Trait Loci, Genes, Plant, Sequence Rendering, F30 - Génétique et amélioration des plantes, MESH: Genotype, Evolution, Molecular, MESH: In Situ Hybridization, 1311 Genetics, Genetic, Gene Expression Regulation, Plant, MESH: Models, MESH: Evolution, Genetics, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, MESH: Genome, Theobroma cacao, [SDV.BV] Life Sciences [q-bio]/Vegetal Biology, cocoa statistics, In Situ Hybridization, genomics and proteomics, cacaoyer, Cell Nucleus, Cacao, Models, Genetic, theobroma, Homozygote, sequence annotation, MESH: DNA, Molecular, Plant, F70 - Taxonomie végétale et phytogéographie, DNA, MESH: Gene Expression Regulation, MESH: Quantitative Trait Loci, MESH: Genes, MESH: DNA Transposable Elements, http://aims.fao.org/aos/agrovoc/c_7713, DNA Transposable Elements, cacao genome, Genome, Plant, MESH: Homozygote
MESH: Cell Nucleus, 570, Genotype, MESH: Cacao, Quantitative Trait Loci, Genes, Plant, Sequence Rendering, F30 - Génétique et amélioration des plantes, MESH: Genotype, Evolution, Molecular, MESH: In Situ Hybridization, 1311 Genetics, Genetic, Gene Expression Regulation, Plant, MESH: Models, MESH: Evolution, Genetics, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, MESH: Genome, Theobroma cacao, [SDV.BV] Life Sciences [q-bio]/Vegetal Biology, cocoa statistics, In Situ Hybridization, genomics and proteomics, cacaoyer, Cell Nucleus, Cacao, Models, Genetic, theobroma, Homozygote, sequence annotation, MESH: DNA, Molecular, Plant, F70 - Taxonomie végétale et phytogéographie, DNA, MESH: Gene Expression Regulation, MESH: Quantitative Trait Loci, MESH: Genes, MESH: DNA Transposable Elements, http://aims.fao.org/aos/agrovoc/c_7713, DNA Transposable Elements, cacao genome, Genome, Plant, MESH: Homozygote
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