Control of ciliation in embryogenesis

descriptionPublicationkeyboard_double_arrow_right Article 30 Jan 2015 English Publisher:Springer Science and Business Media LLCJournal:Nature Cell Biology, volume 17, pages 109-111 (issn: 1465-7392, eissn: 1476-4679,

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Authors: Anna S, Nikonova; Erica A, Golemis;

doi: 10.1038/ncb3103

pmid: 25633272

Control of ciliation in embryogenesis

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Abstract

The protrusion of cilia into extracellular space provides cells with sensors of localized environmental cues that include fluid flow, mechanical force and important growth factors such as Hedgehog. Live imaging has now captured the initial appearance of cilia during embryogenesis, and defined lineage-specific determinants that restrict extra-embryonal ciliogenesis.

Related Organizations

Fox Chase Cancer Center
United States

Keywords

Pregnancy, Animals, Cell Lineage, Female, Cilia, Embryo, Mammalian

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