Molecular dissection of the secretory pathway

descriptionPublicationkeyboard_double_arrow_right Article 30 Jan 1992 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 355, pages 409-415 (issn: 0028-0836, eissn: 1476-4687,

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Authors: J E, Rothman; L, Orci;

doi: 10.1038/355409a0

pmid: 1734280

Molecular dissection of the secretory pathway

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Abstract

A combination of biochemistry in animal cell-free systems and genetics in yeast is revealing the molecular machinery of the secretory pathway of eukaryotes. Transporting vesicles have a simple coat structure and employ a general mechanism for fusion that is conserved in evolution.

Related Organizations

University of Geneva
Switzerland
Kettering University
United States

Keywords

Molecular Sequence Data, Golgi Apparatus, Intracellular Membranes, Saccharomyces cerevisiae, Endoplasmic Reticulum, Membrane Fusion, Models, Biological, Cell Physiological Phenomena, Animals, Amino Acid Sequence, Signal Transduction

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