Mutation detection

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1991 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 353, pages 582-583 (issn: 0028-0836, eissn: 1476-4687,

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Authors: R G, Cotton; A D, Malcolm;

doi: 10.1038/353582a0

pmid: 1922369

Mutation detection

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Abstract

The detection and characterization of mutations in genes has become a major area of interest in many areas of biology. Such variation may account for speciation, tumour formation, drug resistance, as well as the more obvious nature of inherited disease.

Related Organizations

Royal Children's Hospital
Australia

Keywords

Electrophoresis, Base Sequence, Hydrolysis, DNA Mutational Analysis, Nucleic Acid Denaturation, Polymerase Chain Reaction, Genes, Animals, Humans, Oligonucleotide Probes

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